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Facts about Ovarian Hyperstimulation Syndrome (OHSS)

INTRODUCTION

The medications used to stimulate your ovaries may cause side effects. These side effects can range from mild to severe. Excessive stimulation of the ovaries is called ovarian hyperstimulation. This may require removing some of the fluid in the physicians office and/or a hospital stay in approximately 1 % of patients. Be aware of body changes and ask your physician or nurse if you have any questions or concerns. You may have symptoms of mild hyperstimulation during your treatment cycle, however, moderate and severe symptoms usually occur 6-8 days after treatment ends.

Signs and Symptoms
Why it Happens
What to Do
Mild- You may experience:- Abdominal bloating and feeling of fullness- Nausea- Diarrhea- Slight weight gain This may be due to:- Ovaries are larger than normal, tender and fragile- High level so estrogen (E2) and progesterone in the bloodstream may upset your digestive system and fluid balance causing bloating. Recommended treatment:- Avoid sexual intercourse- Do not have a vaginal (pelvic) exam other than by one of our physicians- Reduce activities, no heavy lifting, straining or exercise- Drink clear fluids, flat coke, ginger ale, cranberry juice, Gatorade or Ensure
Moderate- may also experience:- Weight gain of greater than 2 lbs. per day (excessive weight gain)- Increased abdominal measurement causing clothes to feel tight- Vomiting & diarrhea- Urine is darker and amount is less- Skin/hair may feel dry- Thirst This may be due to:- High levels of hormones in the bloodstream upset the digestive system- Fluid imbalance causes dehydration because body fluids collect in the abdomen and other tissues- This fluid collection causes severe bloating As noted above plus:- Call nurses- You may need to be seen by a physician who will do an ultrasound- Record your weight twice daily- Record the number of times you urinate each day- Contact office if you note a five pound weight gain over the previous 24 hours, note a drop in the frequency of urination (~50%), or increasing pelvic pain
Severe- You may also experience:- Fullness/bloating up above the belly button- Shortness of breath- Urination has reduced or stopped and become darker- Calf pains and chest pains- Marked abdominal bloating or distention- Lower abdominal pain This may be due to:- Extremely large ovaries- Fluid collects in lungs and/or abdominal cavity, as well as in tissues- The risk of abnormal blood clotting increases As noted above plus:- Notify the physician on call- You may need to be assessed at the hospital or the physician's office- Excess fluid may need to be removed from your abdominal cavity

 

 


 




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